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Showing 1–1 of 1 articles · Keyword: wildtype AAV infection Clear keyword

Biotechnology journal2026ResearchNon-viral Gene Delivery

1. Comparison of Wildtype and Recombinant Adeno-Associated Virus (AAV) Production Reveals Distinct Productivity and Content Ratio Profiles

Alfieri S, Lee Kh

Recombinant adeno-associated virus is a leading viral vector for gene therapy. However, recombinant adeno-associated virus production systems have low titer and content ratio (ratio of genome-containing to total adeno-associated virus capsids), making it difficult to generate the large number of vector genomes…

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