News

What is happening at Brilliant Blue — and around it

Company Updates covers news from Brilliant Blue Biosciences. Research & Industry News highlights relevant developments published by external sources, summarised and attributed to them.

External21 May 2025

Scientists design gene delivery systems for cells in the brain and spinal cord

Research teams have created a versatile set of gene delivery systems that can reach different neural cell types in the human brain and spinal cord with exceptional accuracy. These delivery systems are a significant step toward future precise gene therapy to the brain that could safely control errant brain activity with high precision. In contrast, current therapies for brain disorders mostly treat only symptoms.

Source: ScienceDaily

Gene Delivery & Transfection

External25 April 2025

Structure dictates effectiveness, safety in nanomedicine

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue this precise control should be applied to optimize new nanomedicines.

Source: ScienceDaily

Drug Delivery & Nanomedicine

External9 April 2025

Engineering smart delivery for gene editors

A research team has developed an advanced delivery system that transports gene-editing tools based on the CRISPR/Cas9 gene-editing system into living cells with significantly greater efficiency than before. Their technology, ENVLPE, uses engineered non-infectious virus-like particles to precisely correct defective genes -- demonstrated successfully in living mouse models that are blind due to a mutation.

Source: ScienceDaily

Gene Delivery & Transfection

External17 February 2025

New lipid nanoparticle platform delivers mRNA to the brain through the blood-brain barrier

Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature of the blood-brain barrier.

Source: ScienceDaily

Gene Delivery & Transfection Lipid Nanoparticles & RNA Therapeutics Drug Delivery & Nanomedicine

External28 January 2025

Escaping the endosome: Bend lipids improve LNP mRNA delivery and gene editing

A new class of lipids improve the rates at which lipid nanoparticles (LNPs) successfully deliver RNA therapeutics and gene editing tools, promising to increase their effectiveness of such treatments.

Source: ScienceDaily

Gene Delivery & Transfection Lipid Nanoparticles & RNA Therapeutics

External13 January 2025

DNA nanorobots can alter artificial cells

Scientists have succeeded in controlling the structure and function of biological membranes with the help of 'DNA origami'. The system they developed may facilitate the transportation of large therapeutic loads into cells. This opens up a new way for the targeted administration of medication and other therapeutic interventions. Thus, a very valuable instrument can be added to the toolbox of synthetic biology.

Source: ScienceDaily

Drug Delivery & Nanomedicine

External22 November 2024

Cooking up a breakthrough: Engineers refine lipid nanoparticles for better mRNA therapies

Engineers have cooked up a new way to improve mRNA delivery, developing an optimal 'recipe' for ionizable lipids -- key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies. The method mirrors the iterative process of developing a culinary dish and may lead to safer, more effective mRNA vaccines and therapeutics.

Source: ScienceDaily

Gene Delivery & Transfection

External13 November 2024

An advance toward inhalable mRNA medications, vaccines

Most people don't enjoy getting shots for treatments or vaccines. So, researchers are working to create more medicines, such as those made from messenger RNA (mRNA), that can be sprayed and inhaled. A study reports steps toward making inhalable mRNA medicines a possibility.

Source: ScienceDaily

Gene Delivery & Transfection Drug Delivery & Nanomedicine

Let's engineer the next delivery breakthrough together

We co-develop nanocarrier and biosensing programmes with pharma, biotech and academic groups — from target selection through scale-up.

ResearchersRequest a technical consultationTalk formulation, characterisation or assay design with one of our scientists.Industry partnersExplore co-developmentFeasibility studies, co-development programmes and licensing.InvestorsExplore the market opportunitySourced market sizes, pipeline, investment and deal data for genetic medicine delivery.