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571 articles

Research Review

Showing 1–1 of 1 articles · Keyword: CRISPR-Cas genome editing Clear keyword

Nanomedicine (London, England)2026ReviewNon-viral Gene Delivery

1. Dual-vector nanoengineered mRNA-CRISPR delivery systems for precision gene therapy in choroidal melanoma

Thakur Sk, Malviya R, Chandra P, Sridhar Sb, Shareef J, Wadhwa T

Choroidal melanoma is the most common primary intraocular malignancy, and effective gene therapy remains limited by ocular barriers, tumor heterogeneity, and inefficient nucleic acid delivery. This review critically analyses the molecular rationale, engineering principles, emerging nanoarchitectures, biological…

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