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Showing 1–1 of 1 articles · Keyword: Diabetic cataract Clear keyword

International journal of biological macromolecules2026ResearchDrug Delivery

1. Hydrophobicity-tuned oleic acid-functionalized chitosan nanoparticles for sustained ocular delivery of dapagliflozin in diabetic cataract

Lin Zi, Yeh Tc, Sun Gc, Chen Yy, Cheng Pw

Chitosan-based biological macromolecules provide a versatile platform for ocular drug delivery, but their hydrophilic nature limits the encapsulation and sustained release of hydrophobic therapeutics. Here, we designed oleic acid-functionalized chitosan nanoparticles (OA-CS NPs) with tunable hydrophobicity by varying…

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