Materials today. Bio2026ReviewNon-viral Gene Delivery
1. Progress and applications of microneedle-based gene therapy
Shen Y, Ye X, Chen Q, Yu D, He L, Lei L, Et Al.
Gene therapy holds considerable promise for treating a wide range of intractable diseases through the modification of specific genes. However, gene therapeutics such as plasmid DNA, messenger RNA, and CRISPR-based systems are susceptible to degradation, face challenges in crossing cellular barriers, and may induce…
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