Articles

Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

391 articles

Keyword: Nucleic acid deliveryClear keyword

Nature Reviews Drug Discovery2024ReviewNon-viral Gene DeliveryDrug Delivery

1. The 60-year evolution of lipid nanoparticles for nucleic acid delivery

Pr Cullis, Pl Felgner

This historical review traces lipid-based gene delivery from cationic lipoplexes to ionizable lipid nanoparticles, connecting foundational research with approved mRNA vaccines and siRNA therapy.

Lipid nanoparticles Nucleic acid delivery Lipoplexes Ionizable lipids mRNA vaccines Patisiran Gene therapy

Read the article

Let's engineer the next delivery breakthrough together

We co-develop nanocarrier and biosensing programs with pharma, biotech and academic groups — from target selection through GMP supply.

Start a conversation Explore the pipeline