Articles

Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

571 articles

Research Review

Showing 1–6 of 6 articles · Keyword: Targeted drug delivery Clear keyword

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2026ReviewDrug Delivery

1. Liposomal and liposome-based formulations of pentacyclic triterpenoids in cancer nanomedicine: A critical appraisal of preclinical progress and future perspectives

Babaei M, Miroliaei M

Pentacyclic triterpenoids (PTs) comprise a broad range of multifunctional plant-derived compound that serve as attractive scaffolds for the development of anticancer drugs. Their modes of action range from triggering apoptosis to modulating oncogenic signaling pathways and the tumor microenvironment. Despite these…

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Pharmaceutics2026ReviewDrug Delivery

2. Cell Membrane-Coated Nanoparticles as Biomimetic Drug Delivery Systems: Design, Therapeutic Applications, and Translational Challenges

Jacob S, Varkey Nr, Rao R, Shinu P, Khanam R

Biomimetic cell membrane-coated nanoparticles (CM-NPs) have emerged as a promising class of nanocarriers that integrate the tunable physicochemical properties of engineered nanoparticles with selected biological features of naturally derived cell membranes.

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Cancers2026ReviewNon-viral Gene DeliveryDrug Delivery

3. Drug Delivery Systems for Breast Cancer Treatment: From Design Principles to Clinical Translation

Sescu Va, Condriuc Ips, Spridon Lg, Cadinoiu An, Miron L, Atanase Li, Et Al.

Breast cancer is the most frequently diagnosed malignancy worldwide and remains a major cause of cancer-related mortality among women. Despite advances in screening, molecular classification, and systemic therapies, treatment of advanced and metastatic disease remains challenging because of tumor heterogeneity…

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ACS nanoscience Au2026ResearchNon-viral Gene DeliveryDrug Delivery

4. Lipid Nanoparticles at the Crossroads of Chemistry and Medicine: A Tutorial

Rogado Mt, Wang A, Zeng S, Wang Z, Burda C

Lipid nanoparticles (LNPs) have risen to the forefront of modern therapeutics by enabling the clinical success of COVID-19 mRNA vaccines. In order for them to function as drug delivery vesicles, LNPs must have scalable, tunable, and targeted nanoscale platforms whose strengths in versatility, performance, and…

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Drug metabolism and bioanalysis2026ReviewNon-viral Gene DeliveryDrug Delivery

5. Biomaterial-Based Drug Delivery Systems: Bridging Advances and Applications in Regenerative Medicine

Ansari I, Yadav S, Prajapati S

In regenerative medicine, biomaterial-based medication delivery systems are a gamechanger because they allow for the restoration of function and the healing of damaged tissues. This study aims to examine the potential of synthetic and natural biomaterials for the delivery of medications and the regeneration of…

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Journal of biomaterials science. Polymer edition2026ReviewNon-viral Gene DeliveryDrug Delivery

6. Progress in polymeric nanoparticle-based treatment approaches for Wnt β-catenin pathway modulation and adenomatous polyposis coli mutant colorectal cancer

Maheshwari T, Bhattacharya S, Singh D

About 80-90% of sporadic instances of colorectal cancer (CRC) are caused by mutations in the adenomatous polyposis coli (APC) gene, which is one of the earliest and most common molecular events. The constitutive activation of the Wnt/β-catenin signalling pathway caused by APC dysfunction promotes unchecked cellular…

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