Articles

Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

601 articles

Research Review

Showing 1–2 of 2 articles · Keyword: blood–brain barrier Clear keyword

Frontiers in immunology2026ReviewNon-viral Gene DeliveryDrug Delivery

1. Intranasal nano-immunotherapy for glioma: bypassing the blood-brain barrier, reprogramming the immune microenvironment, and bridging preclinical validation

Li L, Wu M, Li L

Glioma, particularly glioblastoma, remains difficult to treat because of limited drug penetration across the blood-brain barrier, profound immune suppression, and insufficient intracranial exposure of systemic immunotherapies. Intranasal nano-immunotherapy is being explored as a potential strategy that may integrate…

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International journal of pharmaceutics: X2026ReviewDrug Delivery

2. Precision engineering of nanocarriers for transport across complex biological barriers

Acharya R, Komedchikova E, Choi Y, Yang J, Kim J, Son J, Et Al.

Biological barriers are essential for maintaining tissue homeostasis and protecting organs from harmful external agents; however, they also represent major obstacles to the efficient delivery of therapeutic agents. The blood-brain barrier, ocular barriers, mucosal barriers, and vascular endothelial barriers exhibit…

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