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Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

571 articles

Research Review

Showing 1–2 of 2 articles · Keyword: immunogenicity Clear keyword

Advanced drug delivery reviews2026ReviewDrug Delivery

1. Anti-PEG antibodies in drug delivery: From origins to mitigation strategies

Ding T, Fu J, Zhao X, Lu H, Zhan C

Poly(ethylene glycol) (PEG) is a cornerstone excipient in drug delivery, widely used to prolong circulation duration and improve the therapeutic efficacy of protein therapeutics and nanomedicines. However, both pre-existing and treatment-induced anti-PEG antibodies have been increasingly recognized during clinical…

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Molecular therapy. Advances2026ReviewNon-viral Gene Delivery

2. Stealthy lentiviral vectors: Breaking the barriers to systemic in vivo gene delivery

Keating Al, Carlisle Rc, Mitrophanous Ka, Seymour Lw, Fisher Kd

Lentiviral vector (LVV)-mediated chimeric antigen receptor (CAR)-T cell therapy has transformed the landscape for blood cancer treatment through genetic modification of patients' T cells. Yet, the complexity of the manufacturing process makes this therapy inaccessible for many patients. Systemic intravenous delivery…

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