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Showing 1–1 of 1 articles · Keyword: lentiviral vectors Clear keyword

Molecular therapy. Advances2026ReviewNon-viral Gene Delivery

1. Stealthy lentiviral vectors: Breaking the barriers to systemic in vivo gene delivery

Keating Al, Carlisle Rc, Mitrophanous Ka, Seymour Lw, Fisher Kd

Lentiviral vector (LVV)-mediated chimeric antigen receptor (CAR)-T cell therapy has transformed the landscape for blood cancer treatment through genetic modification of patients' T cells. Yet, the complexity of the manufacturing process makes this therapy inaccessible for many patients. Systemic intravenous delivery…

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