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586 articles

Research Review

Showing 1–1 of 1 articles · Keyword: siRNA therapeutics Clear keyword

Expert opinion on drug delivery2026ReviewNon-viral Gene DeliveryDrug Delivery

1. siRNA therapeutics: from hepatic delivery to extrahepatic targeting

Wang N, Meng L, Shi Jx, Bartneck M

Small interfering RNA (siRNA) has progressed from an experimental gene-silencing tool to an established therapeutic modality through advances in chemical modification and delivery. Lipid nanoparticles (LNP) and N-acetylgalactosamine (GalNAc)-siRNA conjugates have driven this clinical translation, particularly for…

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