1. Stimuli-responsive CRISPR-based genome editing delivery system for cancer treatment: A review of fundamentals and applications
Jiang Y, Sun R, Zhang J, Wang C, Chen X, Wu D
Cancer remains a leading cause of mortality worldwide. Conventional modalities, namely surgery, radiotherapy, chemotherapy, and immunotherapy, continue to face substantial limitations. The advent of gene therapy, particularly CRISPR-based genome editing, offers new opportunities to overcome these barriers.
- CRISPR-based genome editing
- Cancer therapy
- Drug delivery system
- Nanocarriers
- Stimuli-responsive
- Tumor microenvironment
