Articles

Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

391 articles

Keyword: Liver deliveryClear keyword

Molecular Therapy Methods & Clinical Development2025ReviewNon-viral Gene Delivery

1. Rational design of lipid nanoparticles for enabling gene therapies

Ca Brimacombe, Ja Kulkarni, Mhy Cheng, K An, D Witzigmann, Pr Cullis

A review of the physical principles and development history behind siRNA lipid nanoparticles for liver gene silencing and mRNA lipid nanoparticles for protein expression.

Lipid nanoparticles Gene therapy Rational design siRNA mRNA Liver delivery Protein expression

Read the article

Let's engineer the next delivery breakthrough together

We co-develop nanocarrier and biosensing programs with pharma, biotech and academic groups — from target selection through GMP supply.

Start a conversation Explore the pipeline