Articles

Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

586 articles

Research Review

Showing 1–4 of 4 articles · Keyword: cancer therapy Clear keyword

Pharmaceutics2026ReviewDrug Delivery

1. Cell Membrane-Coated Nanoparticles as Biomimetic Drug Delivery Systems: Design, Therapeutic Applications, and Translational Challenges

Jacob S, Varkey Nr, Rao R, Shinu P, Khanam R

Biomimetic cell membrane-coated nanoparticles (CM-NPs) have emerged as a promising class of nanocarriers that integrate the tunable physicochemical properties of engineered nanoparticles with selected biological features of naturally derived cell membranes.

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Nanomaterials (Basel, Switzerland)2026ReviewDrug Delivery

2. Self-Monitoring Theranostic Nanomaterials for Biomedical Imaging and Cancer Therapy: Real-Time Visualization of Biodistribution, Payload Release, and Therapeutic Response

Choi C, Seo D, Park J, Yu D, Song S, Yu S, Et Al.

Theranostic nanomedicines integrate therapeutic delivery with diagnostic imaging, but many conventional platforms primarily visualize nanocarrier localization and provide limited information on whether the therapeutic payload has been released, the intended treatment mechanism has been activated, or a meaningful…

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Nature Reviews Immunology2019ReviewNon-viral Gene Delivery

3. DNA-Stimulated Cell Death: Implications for Host Defence, Inflammatory Diseases and Cancer

Søren R. Paludan, Line S. Reinert, Veit Hornung

DNA in abnormal cellular compartments (cytosol, endosomes, micronuclei) is a potent danger signal for the innate immune system, primarily known for inducing type I interferons and IL-1β. More recently, it has become clear that cytosolic DNA also triggers various forms of programmed cell death (PCD), but the pathways…

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Advanced Drug Delivery Reviews2015ReviewNon-viral Gene Delivery

4. In Vivo Delivery of miRNAs for Cancer Therapy: Challenges and Strategies

Yunching Chen, Dong-Yu Gao, Leaf Huang

miRNAs can simultaneously regulate multiple cancer-related genes, making them attractive therapeutic agents or targets. However, efficient, specific, and safe systemic delivery of therapeutic miRNAs in vivo remains a major challenge due to rapid degradation, poor tumour penetration, immunotoxicity, endosomal…

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