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Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

706 articles

Showing 1–2 of 2 articles · Keyword: DNA delivery Clear keyword

ACS applied materials & interfaces2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Light-Responsive Hybrid Lipid Nanoparticles with Gold Nanorods for Light-Triggered DNA Delivery

Quagliarini E, Petronella F, Digiacomo L, Miglietta S, Buccini L, Mura F, Et Al.

Gene therapy is a cutting-edge strategy for treating, preventing, and potentially eradicating a wide range of diseases. Its success is critically dependent on the transfection efficiency of gene delivery systems. In this context, lipid nanoparticles (LNPs) are widely investigated for the delivery of plasmid DNA…

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Advances in Colloid and Interface Science2026ReviewNon-viral Gene DeliveryDrug Delivery

2. Advances in lipids design for LNP-mediated DNA and RNA delivery

D Zhi, A Halemaimaiti, B Dai, H Li, H Wang, Z Zhang, J Yu, S Zhang

This review examines how lipid structure and formulation affect the delivery of DNA, mRNA and siRNA by lipid nanoparticles, while assessing tissue targeting, safety and clinical translation challenges.

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