Articles

Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

391 articles

Keyword: Tissue targetingClear keyword

Advances in Colloid and Interface Science2026ReviewNon-viral Gene DeliveryDrug Delivery

1. Advances in lipids design for LNP-mediated DNA and RNA delivery

D Zhi, A Halemaimaiti, B Dai, H Li, H Wang, Z Zhang, J Yu, S Zhang

This review examines how lipid structure and formulation affect the delivery of DNA, mRNA and siRNA by lipid nanoparticles, while assessing tissue targeting, safety and clinical translation challenges.

Lipid nanoparticles DNA delivery RNA delivery Ionizable lipids Gene therapy Tissue targeting SORT

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