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Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

706 articles

Research Review

Showing 1–2 of 2 articles · Keyword: RNA delivery Clear keyword

Angewandte Chemie (International ed. in English)2026ResearchNon-viral Gene DeliveryDrug Delivery

1. Supramolecular Pretargeting Lipid Nanoparticles Based on Host-Guest Recognition Potentiate Cancer Immunotherapy by Reprogramming Tumor Microenvironment

Gan J, Wang Y, Li M, Cui S, Zhu L, Yu X, Et Al.

Lipid nanoparticles (LNPs) have emerged as a promising platform for gene/drug delivery in cancer therapy, however their nonspecific biodistribution and extensive hepatosplenic sequestration result in insufficient intratumoral accumulation, thereby undermining the therapeutic efficacy. Here, we establish a sequential…

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Advances in Colloid and Interface Science2026ReviewNon-viral Gene DeliveryDrug Delivery

2. Advances in lipids design for LNP-mediated DNA and RNA delivery

D Zhi, A Halemaimaiti, B Dai, H Li, H Wang, Z Zhang, J Yu, S Zhang

This review examines how lipid structure and formulation affect the delivery of DNA, mRNA and siRNA by lipid nanoparticles, while assessing tissue targeting, safety and clinical translation challenges.

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