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Research Review

Showing 1–1 of 1 articles · Keyword: Patisiran Clear keyword

Nature Reviews Drug Discovery2024ReviewNon-viral Gene DeliveryDrug Delivery

1. The 60-year evolution of lipid nanoparticles for nucleic acid delivery

Pr Cullis, Pl Felgner

This historical review traces lipid-based gene delivery from cationic lipoplexes to ionisable lipid nanoparticles, connecting foundational research with approved mRNA vaccines and siRNA therapy.

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