Articles

Papers, explained in our own words

Every entry summarises what the study set out to test, what it found and why it changes how we design delivery systems. Browse research and reviews or search the collection.

586 articles

Research Review

Showing 1–3 of 3 articles · Keyword: receptor-mediated transcytosis Clear keyword

International journal of pharmaceutics: X2026ReviewDrug Delivery

1. Precision engineering of nanocarriers for transport across complex biological barriers

Acharya R, Komedchikova E, Choi Y, Yang J, Kim J, Son J, Et Al.

Biological barriers are essential for maintaining tissue homeostasis and protecting organs from harmful external agents; however, they also represent major obstacles to the efficient delivery of therapeutic agents. The blood-brain barrier, ocular barriers, mucosal barriers, and vascular endothelial barriers exhibit…

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Expert opinion on drug delivery2026ReviewDrug Delivery

2. Apolipoproteins in nanoparticle-mediated brain drug delivery: promise, mechanisms, and misconceptions

Gelperina S, Wacker Mg

Apolipoprotein E (apoE) plays a context-dependent role in nanomedicine for central nervous system drug delivery. It can facilitate cerebral endothelial recognition and increase brain exposure in nanoparticle systems while simultaneously promoting hepatic uptake, challenging its traditional interpretation as a…

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BioDrugs2026ReviewNon-viral Gene DeliveryDrug Delivery

3. Recent Developments in Lipid Nanoparticle-Mediated Delivery of Biotherapeutics and Gene Therapy Across the Blood-Brain Barrier

U Iqbal, Rw Hwang, Wj Costain

A review of blood–brain barrier transport mechanisms and emerging lipid nanoparticle strategies for carrying nucleic acid and other complex therapies into the central nervous system.

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